In 1918, after the October Revolution, the Yusupov Palace was expropriated, and the art objects from the palace were sold or transmitted to the State Hermitage. Since 1925 the Teachers' House was housed in the palace. In 1958 the interiors of the palace were badly damaged by fire. It took several years to restore the rooms and the halls of the Yusupov palace. In 1987 the theater of the palace was opened to the public: it became the place for music concerts and literature evening arrangements. Nowadays the visitors can admire the splendor interiors of one of the most beautiful palaces in Saint Petersburg .

The Yusupov Palace features original interiors of the 19th-beginning of the 20th centuries. The rooms are decorated in various styles: baroque (the theater), Empire style (gala halls), Oriental style (the Turkish study), neoclassicism (some rooms of the ground floor) and others. The interiors amaze with rich decorations that includes paintings, carving, marble, mirrors, crystal chandeliers, silk, exquisite furniture and so forth. The Yusupov family possessed extensive collections of paintings, sculptures and applied art objects. Some of them are on the display in the palace exposition.

The palace is worth visiting not only as one of the best monuments of the palace architecture of the 19th - beginning of the 20th century but also from the historical point of view.